2-[2-(methylthio)phenoxy]Acetic acid
2-[2-(Methylsulfanyl)phenoxy]acetic acid
CAS: 3395-40-2
Molecular Formula: C9H10O3S
2-[2-(methylthio)phenoxy]Acetic acid - Names and Identifiers
2-[2-(methylthio)phenoxy]Acetic acid - Physico-chemical Properties
| Molecular Formula | C9H10O3S |
| Molar Mass | 198.24 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Melting Point | 167～168℃ |
| Boling Point | 345.7±22.0 °C(Predicted) |
| pKa | 3.16±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | IRRITANT |
| MDL | MFCD09972274 |
2-[2-(methylthio)phenoxy]Acetic acid - Introduction
2-[2-(Methylsulfanyl)phenoxy]acetic acid, Chinese name is 2-[2-(methylthio) phenoxy]acetic acid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder.
-Molecular formula: C10H12O3S.
-Molecular weight: 220.27g/mol.
-Melting point: about 110-115 ℃.
-Solubility: It has high solubility in water.
Use:
- 2-[2-(methylthio) phenoxy] acetic acid is commonly used as an intermediate in medicinal chemistry.
-It is a synthetic precursor of a commonly used glyphosate herbicide. Glyphosate herbicides are weed control agents widely used in agriculture.
-In addition, it can also be used to synthesize pesticides, insecticides and other organic compounds.
Preparation Method:
There are many ways to prepare 2-[2-(methylthio) phenoxy] acetic acid, but the most common method is to synthesize the intermediate methylenated phenyl ether:
1. the reaction of p-methyl phenol (2-cresol) with methylenation reagent (such as halogenated alkanes) to generate methylenated phenyl ether.
2. The methylated phenyl ether reacts with an oxidizing agent (such as hydrogen peroxide) and undergoes acidolysis under alkaline conditions to generate 2-[2-(methylthio) phenoxy] acetic acid.
Safety Information:
- 2-[2-(methylthio) phenoxy] acetic acid is less toxic.
-Avoid inhalation, ingestion or contact with skin and eyes.
-in use or storage should pay attention to avoid contact with oxidants, acids and other substances, in order to prevent the occurrence of dangerous reactions.
-Wear appropriate personal protective equipment such as gloves, goggles and face shields when using.
-If poisoning or irritation occurs, seek medical attention immediately.
Nature:
-Appearance: White crystalline powder.
-Molecular formula: C10H12O3S.
-Molecular weight: 220.27g/mol.
-Melting point: about 110-115 ℃.
-Solubility: It has high solubility in water.
Use:
- 2-[2-(methylthio) phenoxy] acetic acid is commonly used as an intermediate in medicinal chemistry.
-It is a synthetic precursor of a commonly used glyphosate herbicide. Glyphosate herbicides are weed control agents widely used in agriculture.
-In addition, it can also be used to synthesize pesticides, insecticides and other organic compounds.
Preparation Method:
There are many ways to prepare 2-[2-(methylthio) phenoxy] acetic acid, but the most common method is to synthesize the intermediate methylenated phenyl ether:
1. the reaction of p-methyl phenol (2-cresol) with methylenation reagent (such as halogenated alkanes) to generate methylenated phenyl ether.
2. The methylated phenyl ether reacts with an oxidizing agent (such as hydrogen peroxide) and undergoes acidolysis under alkaline conditions to generate 2-[2-(methylthio) phenoxy] acetic acid.
Safety Information:
- 2-[2-(methylthio) phenoxy] acetic acid is less toxic.
-Avoid inhalation, ingestion or contact with skin and eyes.
-in use or storage should pay attention to avoid contact with oxidants, acids and other substances, in order to prevent the occurrence of dangerous reactions.
-Wear appropriate personal protective equipment such as gloves, goggles and face shields when using.
-If poisoning or irritation occurs, seek medical attention immediately.
Last Update：2024-04-09 20:52:54
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